Relaxo 25mg | Dantrolene | 10pcs | Order | Buy | Online | ePharma
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Relaxo 25mg 10Pcs

Generic: Dantrolene

Type: Capsule

Pack Size: 10 Pcs

  • Relaxo 25 is a medication used to control spasticity resulting from upper motor neuronal disorders such as stroke, spinal cord injury, cerebral palsy, or multiple sclerosis.
  • It can also prevent malignant hyperthermia during surgery and is administered orally to prevent the recurrence of symptoms after a malignant hyperthermic crisis.
  • However, Relaxo 25 use may cause liver damage, so patients should have liver function tests done before therapy and at intervals during treatment. Patients should also avoid driving or hazardous activities while taking it.

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MRP: ৳ 100 6% Off

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✅ Description:

Relaxo 25, also known as Dantrolene, is a medication used to control spasticity resulting from upper motor neuronal disorders such as stroke, spinal cord injury, cerebral palsy, or multiple sclerosis. It can also prevent malignant hyperthermia during surgery. However, Relaxo 25 should be used with caution as it can cause liver damage and is not effective in treating skeletal muscle spasms resulting from rheumatic disorders. Liver function tests should be done before therapy and at intervals during treatment, and patients should avoid driving or hazardous activities while taking them.

Safety Advices


Alcohol

No information was found.


Pregnancy
CONSULT YOUR DOCTOR

Please consult your doctor before taking Relaxo 25 during pregnancy.


Breastfeeding
CONSULT YOUR DOCTOR

Relaxo 25 should not be used by nursing mothers. Please consult your doctor before taking Relaxo 25.


Driving

No information was found.


Kidney

No information was found.


Liver
CONSULT YOUR DOCTOR

Relaxo 25 may cause liver damage. Before taking Relaxo 25, consult your doctor.

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✔️ Uses of Relaxo 25:
  • Treatment of spinal cord injury
  • Treatment of Stroke
  • Treatment of Cerebral palsy
  • Treatment of Multiple sclerosis
✔️ Side Effects of Relaxo 25:

The most frequently occurring side effects of Relaxo 25 have been drowsiness,

  • Dizziness
  • Weakness
  • General malaise
  • Fatigue
  • Diarrhea
✔️ How to use Relaxo 25:

Take Relaxo 25 according to your doctor's instructions.

✔️ Indications of Relaxo 25:

Relaxo 25 is used to control clinical spasticity resulting from upper motor neuronal disorders, such as stroke, spinal cord injury, cerebral palsy, or multiple sclerosis. It may improve residual function in patients with presumably reversible spasticity. Long-term use of Dantrolene is justified if it reduces painful or disabling spasticity, decreases required nursing care, or relieves bothersome spasticity symptoms. Dantrolene can also be given orally to prevent malignant hyperthermia in known or suspected susceptible patients undergoing surgery. After a malignant hyperthermic crisis, Dantrolene can be administered orally to prevent the recurrence of symptoms. It is not effective in treating skeletal muscle spasms resulting from rheumatic disorders.

✔️ Pharmacology

Dantrolene induces skeletal muscle relaxation by directly affecting the muscle's contractile response beyond the myoneural junction. It likely disrupts the release of calcium from the sarcoplasmic reticulum, leading to the dissociation of excitation-contraction coupling in skeletal muscle.

✔️ Dosage & Administration of Relaxo 25:

For Use in Chronic Spasticity: 

Adults

The following gradual titration schedule is suggested. Some patients will not respond until the higher daily dosage is achieved. Each dosage level should be maintained for seven days to determine the patient's response. If no further benefit is observed at the next higher dose, the dosage should be decreased to the previous lower dose.

  • Starting dose is 25 mg twice per day and it can be increased to 25-50 mg per day per week. The maximum accepted dosage is 400 mg per day.

Pediatric Patients

The following gradual titration schedule is suggested. Some patients will not respond until the higher daily dosage is achieved. Each dosage level should be maintained for seven days to determine the patient's response. If no further benefit is observed at the next higher dose, the dosage should be decreased to the previous lower dose.

  • 0.5 mg/kg once daily for seven days, then 0.5 mg/kg 3 times for 7 days, 1 mg/kg 3 times for 7 days, and 2 mg/kg 3 times a day, Therapy with a dose of 4 times daily may be necessary for some individuals

For Malignant Hyperthermia:

  • Preoperatively: Administer 4 to 8 mg/kg/day of oral Dantrolene in 3 or 4 divided doses for one or two days prior to surgery, with the last dose being given approximately 3 to 4 hours before scheduled surgery with a minimum of water.
  • Post-Crisis Follow-up: Oral Dantrolene should also be administered following a malignant hyperthermia crisis, in doses of 4 to 8 mg/kg per day in four divided doses, for a one to three-day period to prevent recurrence of the manifestations of malignant hyperthermia.
✔️ Interaction

Drowsiness may occur with Dantrolene therapy, and the concomitant administration of CNS depressants such as sedatives and tranquilizing agents may result in further drowsiness. Hepatotoxicity has occurred more often in women over 35 years of age receiving concomitant estrogen therapy. 

✔️ Contraindications

Active hepatic disease, such as hepatitis and cirrhosis.

✔️ Pregnancy & Lactation:

Pregnancy Category C. Dantrolene capsules should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Dantrolene should not be used in nursing mothers

✔️ Precautions & Warnings

Relaxo 25 may cause liver damage, so therapy should be stopped if no benefit is seen within 45 days. Patients should avoid driving or hazardous activities while taking it. Liver function tests should be done before starting therapy and at intervals during treatment. If symptoms of liver disease occur, Dantrolene should be discontinued. Caution is needed in the concomitant use of tranquilizers and in patients with liver or lung problems. Females and those over 35 years old are at higher risk for liver disease with Dantrolene use.

✔️ Storage Conditions

 Store in a cool & dry place, protected from light. 

Frequently Asked Questions (FAQ)

The most frequently occurring side effects of Dantrolene have been drowsiness, dizziness, weakness, general malaise, fatigue, and diarrhea

Dantrolene Sodium is a medication used to treat muscle spasms, particularly in conditions like spasticity, muscle stiffness or rigidity, and muscle spasticity associated with neurological disorders.

Relaxo 25mg works by preventing the release of calcium ions from the sarcoplasmic reticulum in skeletal muscle, which ultimately reduces the amount of contraction that can occur in muscles.

Dantrolene Sodium is commonly used to treat muscle spasms associated with spasticity, spinal cord injuries, cerebral palsy, multiple sclerosis, and stroke.

Relaxo 25mg is available in capsule and injectable form. The dosage and method of administration will depend on the individual's condition and response to treatment.

Individuals with liver disease, a history of malignant hyperthermia, or an allergic reaction to Dantrolene Sodium should not take this medication. It is important to discuss any medical conditions or allergies with a healthcare provider before starting treatment.

Yes, Dantrolene Sodium may interact with other medications, including other muscle relaxants, sedatives, and medications that affect liver enzymes. It is important to inform the healthcare provider of all medications being taken, including over-the-counter and herbal supplements.
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Check our pricing section for Relaxo 25mg 10Pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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